anti- RAB8A antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat
Tested Application	ELISA, WB, IF, IP
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P61006
Gene ID
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites(AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization. Plays an important role in ciliogenesis. Together with MICALL2, may also regulate adherens junction assembly. May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose homeostasis.
Immunogen	RAB8A, member RAS oncogene family
Synonyms	MEL, Oncogene c mel, RAB8, RAB8A, Ras related protein Rab 8A
Recommended dilution	WB: 1:500-1:5000; IP: 1:200-1:2000; IF: 1:10-1:100
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07045(RAB8A antibody) at dilution of 1:1000

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab07045
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- RAB8A antibody. Примечание: