anti- Phospho-VEGF Receptor 2-Y1175 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P35968 | | Gene ID | | | Calculated MW | 250 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas. | | Immunogen | A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2 | | Synonyms | CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2 | | Recommended dilution | WB: 1:500 - 1:1000; IHC: 1:50 - 1:100 | Immunohistochemistry of paraffin-embedded human breast carcinoma tissue slide using FNab09964 at dilution of 1:50
 | HUVE cells were subjected to SDS PAGE followed by western blot with FNab09964 at dilution of 1:600
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab09964 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- Phospho-VEGF Receptor 2-Y1175 antibody. Примечание: |
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