anti- ZEB1 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IP,IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P37275 | | Gene ID | | | Calculated MW | 124 kDa, Observed 210 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Acts as a transcriptional repressor. Inhibits interleukin-2(IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition(EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box(5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs. The calculated molecular weight of ZEB1 is 124 kDa, but the post phosphorylation of protein is about 190-210 kDa. This is a rabbit polyclonal antibody raised against part of the full length of ZEB1 of human. | | Immunogen | zinc finger E-box binding homeobox 1 | | Synonyms | AREB6, BZP, DELTA EF1, delta EF1,, Negative regulator of IL2, NIL 2 A, NIL 2 A zinc finger protein, NIL 2A, NIL2A, TCF 8, TCF8, Transcription factor 8, ZEB, ZEB1, ZFHEP, ZFHX1A | | Recommended dilution | WB: 1:500-1:5000; IP: 1:200-1:2000；IHC: 1:500-1:5000 | Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab09620(ZEB1 Antibody) at dilution of 1:1000
 | MCF7 cells were subjected to SDS PAGE followed by western blot with FNab09620(ZEB1 antibody) at dilution of 1:500
 | | | |
Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab09620 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- ZEB1 antibody.
Примечание: |
|
