| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q8NAP3 |
| Gene ID | |
| Calculated MW | 134 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements(5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner(PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites(CFS) stability in a RBBP6-and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication(PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons(By similarity). |
| Immunogen | zinc finger and BTB domain containing 38 |
| Synonyms | ZBTB38, FLJ31131, FLJ35036, CIBZ, FLJ22332 |
| Recommended dilution | WB: 1:500-1:5000; IHC: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human testis using FNab09593(ZBTB38 antibody) at dilution of 1:50
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09593(ZBTB38 antibody) at dilution of 1:1000
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