anti- XIAP antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat
Tested Application	ELISA, WB, IHC, IF
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P98170
Gene ID
Calculated MW	54 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background	This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti- apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Immunogen	X-linked inhibitor of apoptosis
Synonyms	API3, BIRC4, hIAP 3, hIAP3, hILP, IAP 3, IAP like protein, IAP3, ILP, ILP1, MIHA, X linked IAP, XIAP, XLP2
Recommended dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab09540(XIAP antibody) at dilution of 1:200
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09540(XIAP antibody) at dilution of 1:1000

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab09540
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- XIAP antibody. Примечание: