anti- WTAP antibodyСпецификация| Clonality | monoclonal | | Host | Mouse | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Clone ID | 9D4 | | Isotype | IgG1 | | Form | liquid | | Purification | Protein A+G purification | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | Q15007 | | Gene ID | | | Calculated MW | 49 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724). | | Immunogen | Wilms tumor 1 associated protein | | Synonyms | DKFZp686F20131, Female lethal(2)D homolog, hFL(2)D, KIAA0105, WT1 associated protein, WTAP | | Recommended dilution | WB: 1:1000-1:10000; IHC: 1:50-1:500 | Immunohistochemistry of paraffin-embedded human cervical cancer using FNab09530(WTAP antibody) at dilution of 1:50
 | HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09530(WTAP Antibody) at dilution of 1:2000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab09530 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- WTAP antibody.
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