| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human |
| Tested Application | ELISA, WB |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q9H0E7 |
| Gene ID | |
| Calculated MW | 145 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B(H2BK120ub1) ubiquitination. |
| Immunogen | ubiquitin specific peptidase 44 |
| Synonyms | Deubiquitinating enzyme 44, DKFZp434D0127, FLJ14528, Ubiquitin thiolesterase 44, USP44 |
| Recommended dilution | WB: 1:500-1:5000 |
human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09334(USP44 antibody) at dilution of 1:500
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Наименование: anti- USP44 antibody.