anti- TXNIP antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, IHC, WB, IF | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | Q9H3M7 | | Gene ID | | | Calculated MW | 50 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1(mTORC1). | | Immunogen | thioredoxin interacting protein | | Synonyms | EST01027, HHCPA78, THIF, Thioredoxin binding protein 2, TXNIP, VDUP1 | | Recommended dilution | WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:10-1:100 | Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab09129(TXNIP Antibody) at dilution of 1:200
 | K-562 cells were subjected to SDS PAGE followed by western blot with FNab09129(TXNIP Antibody) at dilution of 1:600
 | | | |
Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab09129 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- TXNIP antibody.
Примечание: |
|
