anti- NR1H3 antibody

Спецификация

Clonality	monoclonal
Host	Mouse
Specificity	Human, Rat
Tested Application	ELISA, WB, IF
Delivery Time	2 to 4 working days
Clone ID	7D2
Isotype	IgG2a
Form	liquid
Purification	Protein A+G purification
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q13133
Gene ID
Calculated MW	48 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism(By similarity). Exhibits a ligand-dependent transcriptional activation activity(PubMed:25661920).
Immunogen	nuclear receptor subfamily 1, group H, member 3
Synonyms	Liver X receptor alpha, LXR a, LXRA, NR1H3, Oxysterols receptor LXR alpha, RLD 1
Recommended dilution	WB: 1:200-1:1000; IF: 1:10-1:100
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab05836(NR1H3 antibody) at dilution of 1:500

Информация для заказа

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab05836
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- NR1H3 antibody. Примечание: