anti- Synaptotagmin-1 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IHC, IP | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P21579 | | Calculated MW | 65 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis(PMID: 8058779). SYT1(synaptotagmin I) was firstly identified as a 65-kDa protein with a wide distribution in neuronal and neurosecretory tissue(PMID: 7298720). Calcium binding to SYT1 participates in triggering neurotransmitter release at the synapse(PMID: 11242035). In addition to regulating exocytosis, SYT1 has also been implicated in endocytosis and neurite outgrowth(PMID: 15492212; 11078930; 10336114). This antibody recognizes endogenous SYT1, which has an experimentally determined molecular mass of 65-68 kDa. An additional band of 47 kDa could also be detected, which is corresponding to the calculated molecular weight of SYT1. | | Immunogen | synaptotagmin I | | Synonyms | DKFZp781D2042, P65, SVP65, Synaptotagmin 1, synaptotagmin I, SYT, SYT1, SytI | | Recommended dilution | WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500 | Immunohistochemistry of paraffin-embedded human liver cancer using FNab08425(SYT1 antibody) at dilution of 1:100
 | human liver tissue were subjected to SDS PAGE followed by western blot with FNab08425(SYT1 antibody) at dilution of 1:1000
 | | | |
Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab08425 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- Synaptotagmin-1 antibody.
Примечание: |
|
