| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse |
| Tested Application | ELISA, WB, IHC, IF |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P09913 |
| Gene ID | |
| Calculated MW | 50-55 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. |
| Immunogen | interferon-induced protein with tetratricopeptide repeats 2 |
| Synonyms | CIG-42, G10P2, IFI54, ISG54 |
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab04137(IFIT2 Antibody) at dilution of 1:50
 |
A431 cells were subjected to SDS PAGE followed by western blot with FNab04137(IFIT2 Antibody) at dilution of 1:300
 |
| | |
