| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, IHC, WB, FC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q9HBX8 |
| Gene ID | |
| Calculated MW | 104 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins(RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor. |
| Immunogen | leucine-rich repeat-containing G protein-coupled receptor 6 |
| Synonyms | FLJ14471, GPCR, LGR6, VTS20631 |
| Recommended dilution | WB: 1:200-1:1000; IHC: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human testis using FNab04766(LGR6 antibody) at dilution of 1:50
 |
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab04766(LGR6 antibody) at dilution of 1:100
 |
| | |
