anti- Integrin alpha-5 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Rat, Mouse, Monkey | | Tested Application | ELISA, WB | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P08648 | | Calculated MW | 120 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881). | | Immunogen | integrin, alpha 5 | | Synonyms | CD49e, FNRA, Integrin alpha 5, Integrin alpha F, ITGA5, VLA 5, VLA5A | | Recommended dilution | WB: 1:500-1:2000 | 3T3-L1 cells were subjected to SDS PAGE followed by western blot withFNab04347(ITGA5 antibody) at dilution of 1:1000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab04347 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: anti- Integrin alpha-5 antibody.
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