| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB,IHC,IF |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P04792 |
| Calculated MW | 27 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | HSPB1, also known as heat shock protein 27(Hsp27), belongs to the small heat shock protein family which is induced in response to environmental challenges or/and developmental transitions. It is also an anti-apoptotic protein that plays crucial roles in tumorigenesis and cell survival and is reported to be an independent prognosis marker for cancer. Recently HSPB1 has been found to be a valuable marker for melanoma. In addition to the predicted 27 kDa, an extra 50-55 kDa representing dimeric form of HSPB1 may also be observed.(21353161) |
| Immunogen | heat shock 27kDa protein 1 |
| Synonyms | Heat shock protein beta 1, HSP 27, Hsp25, HSP27, HSP28, HSPB1 |
| Recommended dilution | WB: 1:500-1:3000; IHC: 1:50-1:500; IF: 1:10-1:100 |
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04044(HSP27 antibody) at dilution of 1:200
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab04044(HSPB1 antibody) at dilution of 1:1000
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