| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human |
| Tested Application | ELISA, WB, IHC, IF |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P57764 |
| Gene ID | |
| Calculated MW | 50-53 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. |
| Immunogen | gasdermin D |
| Synonyms | DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1 |
| Recommended dilution | WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100 |
Immunohistochemistry of paraffin-embedded human skin using FNab03670(GSDMD antibody) at dilution of 1:50
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03670(GSDMD Antibody) at dilution of 1:500
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