anti- liver Arginase antibodyСпецификация| Clonality | monoclonal | | Host | Mouse | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Clone ID | 4A0 | | Isotype | IgG2a | | Form | liquid | | Purification | Protein A+G purification | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P05089 | | Gene ID | | | Calculated MW | 35 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406). | | Immunogen | arginase, liver | | Synonyms | ARG1, Arginase 1, liver Arginase, Liver type arginase | | Recommended dilution | WB: 1:1000-1:8000; IHC: 1:200-1:1000 | Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab04801(ARG1 Antibody) at dilution of 1:50.
 | HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04801(ARG1 Antibody) at dilution of 1:4000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab04801 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- liver Arginase antibody.
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