| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P39060 |
| Calculated MW | 19 kDa, 27 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Endostatin is a naturally-occurring 20-kDa C-terminal fragment derived from COL18A1(also named as KNO). It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. It potently inhibits endothelial cell proliferation and inhibits endothelial cell angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor(bFGF/FGF-2) and vascular endothelial growth factor(VEGF). |
| Immunogen | collagen, type XVIII, alpha 1 |
| Synonyms | Endostatin |
| Recommended dilution | WB: 1:200-1:1000; IHC: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human liver using FNab02762(Endostatin, COL18A1 antibody) at dilution of 1:50
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human liver tissue were subjected to SDS PAGE followed by western blot with FNab02762(Endostatin, COL18A1 antibody) at dilution of 1:500
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