anti- IL-10 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P22301 | | Gene ID | | | Calculated MW | 21 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) | | Background | The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. | | Immunogen | interleukin 10 | | Synonyms | CSIF, IL 10, IL10, IL-10, IL10A, interleukin 10, TGIF | | Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 | Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using FNab04211( IL10 Antibody) at dilution of 1:100
 | Recombinant protein were subjected to SDS PAGE followed by western blot with FNab04211( IL10 Antibody) at dilution of 1:1000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab04211 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- IL-10 antibody.
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