| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IHC, IP, IF, FC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P01130 |
| Gene ID | |
| Calculated MW | 150-160 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE. |
| Immunogen | low density lipoprotein receptor |
| Synonyms | FH, FHC, LDL receptor, LDLR |
| Recommended dilution | WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab04742(LDLR Antibody) at dilution of 1:200 heat mediated antigen retrieved with Sodium Citrate buffer(pH6).
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04742(LDLR antibody) at dilution of 1:300
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