| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, IHC, IF, WB |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P17174 |
| Gene ID | |
| Calculated MW | 43-46 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. |
| Immunogen | glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1) |
| Synonyms | AATC, CAT, GIG18, GOT1, Transaminase A |
| Recommended dilution | WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100 |
Immunohistochemistry of paraffin-embedded human lung cancer using FNab09876(GOT1 antibody) at dilution of 1:100
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09876(GOT1 antibody) at dilution of 1:1000
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