anti- PHD3 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human | | Tested Application | ELISA, WB, IHC, IP | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | Q9H6Z9 | | Calculated MW | 28kd | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | EGLN3, also named as HPH-1, HIF-PH3, HPH-3 and PHD3, is a cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor(HIF) alpha proteins. It hydroxylates a specific proline found in each of the oxygen-dependent degradation(ODD) domains(N-terminal, NODD, and C-terminal, CODD) of HIF1A. It is a regulator of cardiomyocyte and neuronal apoptosis. EGLN3 can be a prognostic marker for gastric cancer. | | Immunogen | egl nine homolog 3 | | Synonyms | Egl nine homolog 3, EGLN3, FLJ21620, HIF PH3, HIF prolyl hydroxylase 3, HIFPH3, HPH 1, HPH 3, PHD3 | | Recommended dilution | WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human brain using FNab06377(EGLN3 antibody) at dilution of 1:50
 | HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab06377(EGLN3 antibody) at dilution of 1:1000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab06377 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- PHD3 antibody.
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