| Clonality | monoclonal |
| Host | Mouse |
| Specificity | Human |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Clone ID | 3C12 |
| Isotype | IgG1 |
| Form | liquid |
| Purification | protein A+G purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P17693 |
| Gene ID | |
| Calculated MW | 38 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance. |
| Immunogen | MHC class I antigen G |
| Synonyms | HLA 6.0, HLA G, HLA G antigen, HLAG, HLA-G, MHC class I antigen G, MHC G |
| Recommended dilution | WB: 1:2000-1:10000; IHC: 1:50-1:200 |
Immunohistochemistry of paraffin-embedded human placenta tissue slide using FNab09952( HLA-G Antibody) at dilution of 1:200
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human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09952( HLA-G Antibody) at dilution of 1:5000
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