anti- KEAP1 antibodyСпецификация| Clonality | monoclonal | | Host | Mouse | | Specificity | Human, Rat | | Tested Application | ELISA, IHC, WB | | Delivery Time | 2 to 4 working days | | Clone ID | 9E2 | | Isotype | IgG2a | | Form | liquid | | Purification | Protein A+G purification | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | Q14145 | | Gene ID | | | Calculated MW | 55-70 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome. | | Immunogen | kelch-like ECH-associated protein 1 | | Synonyms | INRF2, KIAA0132, KLHL19 | Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab04517(KEAP1 antibody) at dilution of 1:100
 | HeLa cells were subjected to SDS PAGE followed by western blot with FNab04517(KEAP1 antibody) at dilution of 1:500
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab04517 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- KEAP1 antibody.
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