| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q9BY41 |
| Gene ID | |
| Calculated MW | 43 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Background | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | histone deacetylase 8 |
| Synonyms | HDACL1 |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
Immunohistochemistry of paraffin-embedded human breast cancer using FNab03805(HDAC8 Antibody) at dilution of 1:100
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mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab03805(HDAC8 antibody) at dilution of 1:1000
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