anti- GLRA1 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P23415 | | Gene ID | | | Calculated MW | 48 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Glycine receptors are ligand-gated chloride channels(PubMed:23994010, PubMed:25730860). Channel opening is triggered by extracellular glycine(PubMed:2155780, PubMed:7920629, PubMed:14551753, PubMed:16144831, PubMed:22715885, PubMed:22973015, PubMed:25973519, PubMed:9009272). Channel opening is also triggered by taurine and beta-alanine(PubMed:16144831, PubMed:9009272). Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization(PubMed:14551753). Plays an important role in the down-regulation of neuronal excitability(PubMed:8298642, PubMed:9009272). Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488). Channel activity is potentiated by ethanol(PubMed:25973519). Potentiation of channel activity by intoxicating levels ot ethanol contribute to the sedative effects of ethanol(By similarity). | | Immunogen | glycine receptor, alpha 1 | | | |
Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab03486 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: anti- GLRA1 antibody.
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