| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P56524 |
| Gene ID | |
| Calculated MW | 130 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Background | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. |
| Immunogen | histone deacetylase 4 |
| Synonyms | KIAA0288 |
| Recommended dilution | WB: 1:500 - 1:1000; IHC: 1:50 - 1:100 |
Immunohistochemistry of paraffin-embedded human stomach using FNab03800(HDAC4 antibody) at dilution of 1:100
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab03800(HDAC4 antibody) at dilution of 1:1000
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