anti- Collagen Type IV antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human | | Tested Application | ELISA, IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P08572 | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Type IV collagen is the major structural component of glomerular basement membranes(GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and-9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins. | | Immunogen | collagen, type IV, alpha 2 | | Synonyms | COL4A2, Collagen alpha 2(IV) chain, Collagen Type IV, collagen, type IV, alpha 2, DKFZp686I14213, FLJ22259 | | Recommended dilution | IHC: 1:20-1:200 | IHC Image
 | | | |
Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab01844 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- Collagen Type IV antibody.
Примечание: |
|
