anti- FAS/CD95 antibodyСпецификация| Clonality | monoclonal | | Host | Mouse | | Specificity | Human, Mouse | | Tested Application | ELISA, WB, FC,IHC | | Delivery Time | 2 to 4 working days | | Clone ID | 4B6 | | Isotype | IgG2a | | Form | liquid | | Purification | Protein A+G purification | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P25445 | | Calculated MW | 38-45 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Fas(CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor(TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex(DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form(40-55 kDa) of Fas is due to glycosylation. | | Immunogen | Fas(TNF receptor superfamily, member 6) | | Synonyms | ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6 | | Recommended dilution | WB: 1:1000-1:8000; IHC: 1:50-1:500 | Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab03017(FAS/CD95 antibody) at dilution of 1:200.
 | HeLa cells were subjected to SDS PAGE followed by western blot with FNab03017(FAS/CD95 antibody) at dilution of 1:4000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab03017 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- FAS/CD95 antibody.
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