anti- CEP290 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IP, IHC, IF | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | O15078 | | Gene ID | | | Calculated MW | 290 kDa, 150-180 kDa, 80 kDa, 60 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Studies in the Chlamydomonas model system has shown that the ciliary protein CEP290 is a critical component of these Y-link junctions. Additionally, numerous studies have demonstrated that CEP290’s function is critical for IFT—in CEP290 knockdown experiments, many proteins that would normally localize to the cilium fail to do so, and cilium formation is disrupted or absent. Mutations in CEP290 are accountable for cases of nephronophthisis, Leber congenital amaurosis and Joubert syndrome. In IF analtsis of HeLa cells, the white arrows show centrosome and cilium staining. | | Immunogen | centrosomal protein 290kDa | | Synonyms | BBS14, KIAA0373, NPHP6,LCA10, MKS4, Nephrocystin 6, rd16, SLSN6, Tumor antigen se2 2 | | Recommended dilution | WB: 1:200-1:2000; IP: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500 | Immunohistochemistry of paraffin-embedded human placenta using FNab01602(CEP290 antibody) at dilution of 1:50
 | HeLa cells were subjected to SDS PAGE followed by western blot with FNab01602(CEP290 Antibody) at dilution of 1:600
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab01602 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- CEP290 antibody.
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