anti- Caspase 1 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P29466 | | Gene ID | | | Calculated MW | 45-47 kDa, 30 kDa, 35 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta(IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing. | | Immunogen | caspase 1, apoptosis-related cysteine peptidase(interleukin 1, beta, convertase) | | Synonyms | CASP 1, CASP1, Caspase 1, Caspase 1/p20/p10, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1BC, IL1BCE, Interleukin 1 beta convertase, p10, p20, P45 | | Recommended dilution | WB: 1:500-1:2000,IHC: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human spleen tissue slide using FNab01284(Caspase 1 Antibody) at dilution of 1:100
 | Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01284(CASP1 antibody) at dilution of 1:1000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab01284 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- Caspase 1 antibody.
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