| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P42575 |
| Calculated MW | 50 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | This gene encodes a member of the cysteine-aspartic acid protease(caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
|
| Immunogen | caspase 2, apoptosis-related cysteine peptidase |
| Synonyms | CASP 2, CASP2, Caspase 2,ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1 |
| Recommended dilution | WB: 1:500-1:2000; IHC: 1:50-1:200 |
Immunohistochemistry of paraffin-embedded human gastric cancer tissue slide using FNab01287(Caspase 2 Antibody) at dilution of 1:100
 |
HeLa cells were subjected to SDS PAGE followed by western blot with FNab01287(CASP2 antibody) at dilution of 1:500
 |
| | |
