anti- CYP3A4 antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human
Tested Application	ELISA, WB, IHC, FC
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P08684
Gene ID
Calculated MW	60 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen	cytochrome P450, family 3, subfamily A, polypeptide 4
Synonyms	CYP3A3
Recommended dilution	WB: 1:500 - 1:1000; IHC: 1:20 - 1:50; FC :1:20 - 1:50
Immunohistochemistry of paraffin-embedded human liver using FNab02165(CYP3A4 antibody) at dilution of 1:50
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab02165(CYP3A4 antibody) at dilution of 1:1000

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab02165
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- CYP3A4 antibody. Примечание: