| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, IHC, WB, IF |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P20851 |
| Gene ID | |
| Calculated MW | 54 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Background | This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. |
| Immunogen | complement component 4 binding protein, beta |
| Synonyms | C4BP |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100 |
Immunohistochemistry of paraffin-embedded mouse kidney using FNab01114(C4BPB antibody) at dilution of 1:100
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab01114(C4BPB antibody) at dilution of 1:1000
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