anti- CD59 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human | | Tested Application | ELISA, WB, IHC, FC, IF | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P13987 | | Gene ID | | | Calculated MW | 18-20 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Potent inhibitor of the complement membrane attack complex(MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. | | Immunogen | CD59 molecule, complement regulatory protein | | Synonyms | MIC11, MIN1, MIN2, MIN3, MSK21 | Immunohistochemistry of paraffin-embedded human ovary tumor using FNab01489(CD59 antibody) at dilution of 1:100
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab01489 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- CD59 antibody.
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