anti- APTX antibody

Highlight	New Arrivals -2022
Clonality	polyclonal
Host	Rabbit
Specificity	Human
Tested Application	ELISA, WB, IHC
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q7Z2E3
Gene ID
Calculated MW	40 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background	APTX, also named as Aprataxin, is a nuclear protein, present in both the nucleoplasm and the nucleolus, which is a member of the histidine triad (HIT) superfamily. APTX is involved in DNA single-strand break repair, mediating protein-protein interactions with molecules responding to DNA damage. APTX contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain. Loss of function mutations in APTX, the gene encoding for Aprataxin, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, characterized by abnormal movements of the head and eyes.
Immunogen	aprataxin
Synonyms	AOA, AOA1, aprataxin, APTX, AXA1, EAOH, EOAHA, FHA HIT
Recommended dilution	WB: 1:500 - 1:2000; IHC: 1:20 - 1:200

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab10359
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- APTX antibody. Примечание: