anti- ADAR1 antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat, Pig
Tested Application	ELISA, IHC, IF, WB, IP
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P55265
Calculated MW	136 kDa, observed 110 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon(IFN) inducible ?150 kDa protein and a constitutively expressed N-terminally truncated ?110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria(DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).
Immunogen	adenosine deaminase, RNA-specific
Synonyms	ADAR, ADAR1, adenosine deaminase, RNA, DRADA, DSH, DSRAD, G1P1, IFI 4, IFI4, Interferon inducible protein 4, K88dsRBP, p136
Recommended dilution	WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000; IF: 1:20-1:200
Immunohistochemistry of paraffin-embedded human gliomas using FNab00150(ADAR1 antibody) at dilution of 1:50
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00150(ADAR1 Antibody) at dilution of 1:1000

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab00150
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- ADAR1 antibody. Примечание: