anti- AKAP10 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | O43572 | | Gene ID | | | Calculated MW | 74 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase(By similarity). | | Immunogen | A kinase(PRKA) anchor protein 10 | | Synonyms | AKAP10, D AKAP2, AKAP 10, PRKA10, D AKAP 2 | | Recommended dilution | WB: 1:500-1:5000; IHC: 1:20-200 | Immunohistochemistry of paraffin-embedded human cervical cancer using FNab00250(AKAP10 antibody) at dilution of 1:100
 | HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00250(AKAP10 antibody) at dilution of 1:500
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab00250 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- AKAP10 antibody.
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