| Clonality | monoclonal |
| Host | Mouse |
| Specificity | Human |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Clone ID | 8D6 |
| Isotype | IgG2a |
| Form | liquid |
| Purification | Protein A+G purification |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P15309 |
| Gene ID | |
| Calculated MW | 48 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions(pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion(DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling. |
| Immunogen | acid phosphatase, prostate |
| Synonyms | Acid phosphatase, prostate, ACP 3, ACP3, ACPP, PAP, Prostatic acid phosphatase |
| Recommended dilution | WB: 1:200-1:2000; IHC: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human prostate hyperplasia using FNab00102(ACPP antibody) at dilution of 1:50
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human testis tissue were subjected to SDS PAGE followed by western blot with FNab00102(ACPP antibody) at dilution of 1:400
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