| Объем | 100 мкл |
| Синонимы | DNA-repair protein complementing XP-A cells, XPAC, Xeroderma pigmentosum group A complementing protein, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P23025 |
| Иммуноген | Synthesized peptide derived from Internal of human XPA. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.<br/><br/>Gary W. Daughdrill, Nucleic Acids Res., Jul 2003, 31: 4176 - 4183. <br/>Esther M. Hoogervorst, Carcinogenesis, Mar 2003, 24: 613 - 619. <br/>Karen M. Vasquez, PNAS, Apr 2002, 99: 5848. <br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using XPA antibody.
 |
Western blot analysis of extracts from COLO205 cells, using XPA antibody.
 |
Western blot analysis of extracts from COS7 cells (Lane 2), using XPA antiobdy. The lane on the left is treated with systhesized peptide.
 |
| | |
Наименование: XPA Antibody.