| Объем | 100 мкл |
| Синонимы | DKFZp686M05248, MGC102856, MGC42116, p53-inducible ribonucleotide reductase small subunit 2 homolog, p53-inducible ribonucleotide reductase small subunit 2-like protein |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q7LG56 |
| Иммуноген | Synthesized peptide derived from Internal of human RRM2B. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.<br/><br/>Tanaka H., Nature 404:42-49(2000).<br/>Ugai H., Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells, using RRM2B antibody.
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Наименование: RRM2B Antibody.