| Объем | 100 мкл |
| Синонимы | G15, H37, LUCA15, RMB5, RNA binding motif protein 5 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P52756 |
| Иммуноген | Synthesized peptide derived from internal of human RBM5. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.<br/><br/>Bader S., Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.<br/>Timmer T., Genomics 60:238-240(1999).<br/>Oh J.J., Nucleic Acids Res. 27:4008-4017(1999).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HUVEC cells, using RBM5 antibody.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using RBM5 antibody.
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Наименование: RBM5 Antibody.