| Объем | 100 мкл |
| Синонимы | Ran-binding protein 3 (RanBP3), RANBP3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9H6Z4 |
| Иммуноген | Recombinant Human Ran-binding protein 3 protein (1-250AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Ran-binding protein 3 |
| Области исследований | Epigenetics and Nuclear Signaling, Cell biology, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: RANBP3 antibody at 6.4µg/ml
Lane 1: Mouse brain tissue
Lane 2: Hela whole cell lysate
Lane 3: HepG2 whole cell lysate
Lane 4: Jurkat whole cell lysate
Lane 5: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 61, 60, 54 kDa
Observed band size: 61 kDa
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA867162DSR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA867162DSR2HU at dilution of 1:100
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Наименование: RANBP3 Antibody.