PLG AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Activation peptide, Angiostatin, DKFZp779M0222, plasmin, Plasmin heavy chain A | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P00747 | | Иммуноген | Synthesized peptide derived from N-terminal of human PLG. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.<br/><br/>Petersen T.E., J. Biol. Chem. 265:6104-6111(1990).<br/>Forsgren M., FEBS Lett. 213:254-260(1987).<br/>Browne M.J., Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases.<br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cardiovascular,Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells, using PLG antibody.
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Наименование: PLG Antibody.