Phospho-PDGFRA (Tyr849) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CD140a, PDGFR-alpha, PGFRA, kinase PDGFR-alpha, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P16234 | | Иммуноген | Peptide sequence around phosphorylation site of Tyrosine849(S-N-Y(p)-V-S) derived from Human PDGFRa. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. <br/><br/>Rikova K, et al. (2007) Cell 131, 1190-203 <br />Moritz A, et al. (2010) Sci Signal 3, ra64 <br />Guo A, et al. (2008) Proc Natl Acad Sci U S A 105, 692-7 </p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Tyr849 | | Области исследований | Cancer,Cardiovascular,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293 tissue using PDGFRa (Phospho-Tyr849) antibody.The lane on the right is treated with the antigen-specific peptide.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA123585 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-PDGFRA (Tyr849) Antibody.
Примечание: дополнительная информация (на английском языке). |
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