| Объем | 100 мкл |
| Синонимы | MLC-2a, MLC2a, MLRA, MYL7, MYLC2A |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P24844 |
| Иммуноген | Peptide sequence around phosphorylation site of serine 19 (A-T-S(p)-N-V) derived from Human Myosin Light Chain 2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
| Примечание | <p>Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion <br /><br />Janiak A, et al. (2006) Mol Biol Cell. Apr, 17(4): 1606-1619. <br />Croft DR, et al. (2006) Mol Cell Biol. 2 Jun, 26(12): 4612-4627 <br />Li Z, et al. (2006) Mol Cell Biol. Jun, 26(11): 4240-4256</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser19 |
| Области исследований | Cardiovascular,Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells untreated or treated with starvation using Myosin Light Chain 2 (Phospho-Ser19) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Myosin Light Chain 2 (Phospho-Ser19) Antibody (left) or the same antibody preincubated with blocking peptide (right).
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