Phospho-MAP2K7 (Ser271) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | PRKMK7, JNKK2, MKK7, MAP2K7, MP2K7 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O14733 | | Иммуноген | Peptide sequence around phosphorylation site of Serine271(V-D-S(p)-K-A) derived from Human MAP2K7. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 | | Примечание | <p>The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.<br/><br/>Wu Z., Mol. Cell. Biol. 17:7407-7416(1997).<br />Lu X., J. Biol. Chem. 272:24751-24754(1997).<br />Foltz I.N., J. Biol. Chem. 273:9344-9351(1998).</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Ser271 | | Области исследований | Immunology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 3T3 cells treated with insulin using MAP2K7 (Phospho-Ser271) Antibody.The lane on the right is treated with the antigen-specific peptide.
 | Immunohistochemical analysis of paraffin-embedded humanbrain tissue, using MAP2K7 (Phospho-Ser271) antibody (left)or the same antibody preincubated with blocking peptide (right).
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA112719 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-MAP2K7 (Ser271) Antibody.
Примечание: дополнительная информация (на английском языке). |
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