Phospho-IRS1 (Ser636) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | IRS-1, IRS1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P35568 | | Иммуноген | Peptide sequence around phosphorylation site of serine 636 (P-M-S(p)-P-K) derived from Human IRS-1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 | | Примечание | May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit <br/><br/>Ozes ON, et al. (2001) Proc Natl Acad Sci U S A, 98(8): 4640-4645<br/>Tzatsos A, et al. (2006) Mol Cell Biol, 26(1): 63-76<br/>Kadowaki T, et al. (2000) J Clin Invest, 106(4): 459-465<br/>Ozes ON, et al. (2001) Proc Natl Acad Sci U S A, 98(8): 4640-4645<br/>Szanto I, et al. (2000) Proc Natl Acad Sci U S A, 97(5): 2355-2360<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Ser636 | | Области исследований | Neuroscience,Cancer,Cardiovascular,Tags & Cell Markers,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 3T3 cells untreated or treated with Insulin using IRS-1(Phospho-Ser636) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS-1(Phospho-Ser636) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA577877 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-IRS1 (Ser636) Antibody.
Примечание: дополнительная информация (на английском языке). |
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