| Объем | 100 мкл |
| Синонимы | ER, ESR, ESR1, ESTR, ESTRA |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P03372 |
| Иммуноген | Peptide sequence around phosphorylation site of serine 104 (S-V-S(p)-P-S) derived from Human Estrogen Receptor-a. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
| Примечание | Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.<br/><br/>Dittadi, R. et al. (2000) J. Natl. Cancer Inst. 92, 1443-1444.<br/>Muthuswamy, S. K. et al. (1999) Mol. Cell. Biol. 19, 6845-6857.<br/>Qian, X. et al. (1994) Proc. Natl. Acad. Sci. USA 91, 1500-1504.<br/>Kwon, Y. K. et al. (1997) J. Neurosci. 17, 8293-8299.<br/>Klapper, L. N. et al. (2000) Cancer Res. 60, 3384-3388.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser104 |
| Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from MCF-7 cells untreated or treated with E2 and EGF using Estrogen Receptor-a(Phospho-Ser104) Antibody
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Estrogen Receptor-a(Phospho-Ser104) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: Phospho-ESR1 (Ser104) Antibody.