| Объем | 100 мкл |
| Синонимы | ADRB2R, B2AR, adrenergic receptor, beta-2, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P07550 |
| Иммуноген | Peptide sequence around phosphorylation site of serine 346 (R-S-S(p)-L-K) derived from Human Adrenergic Receptor beta2. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.<br /><br />Gao S, Malbon C, Wang HY (2014) J Mol Signal 9, 3 <br />24690384 Curated Info<br />Vistein R, Puthenveedu MA (2013) Proc Natl Acad Sci U S A 110, 15289-94 <br />Gimenez LE, et al. (2012) J Biol Chem 287, 9028-40</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser346 |
| Области исследований | Cardiovascular,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells treated with Nocodazole using Phospho-Adrenergic Receptor beta2 (Ser346) antibody.The lane on the right is treated with the antigen-specific peptide.
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