| Объем | 100 мкл |
| Синонимы | Poly [ADP-ribose] polymerase 2, PARP-2, NAD(+) ADP-ribosyltransferase 2, Poly[ADP-ribose] synthetase 2, pADPRT-2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UGN5 |
| Иммуноген | Synthesized peptide derived from internal of human PARP2. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.<br/><br/>Sugano S., Nat. Genet. 36:40-45(2004).<br/>de Murcia G.M., J. Biol. Chem. 277:23028-23036(2002).<br/>Bennett K.L., Submitted (OCT-2008).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 and HuvEc cells, using PARP2 antibody.
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Наименование: PARP2 Antibody.